Distinguishing direct versus indirect transcription factor-DNA interactions
Transcriptional regulation is largely enacted by transcription factors (TFs) binding DNA. Large numbers of TF binding motifs have been revealed by ChIP-chip experiments followed by computational DNA motif discovery. However, the success of motif discovery algorithms has been limited when applied to...
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Format: | Article |
Language: | English |
Published: |
Cold Spring Harbor Laboratory Press,
2013-02-06T20:56:46Z.
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Subjects: | |
Online Access: | Get fulltext |