Lineage-based identification of cellular states and expression programs

Lineage-based identification of cellular states and expression programs

We present a method, LineageProgram, that uses the developmental lineage relationship of observed gene expression measurements to improve the learning of developmentally relevant cellular states and expression programs. We find that incorporating lineage information allows us to significantly improv...

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Bibliographic Details
Main Authors: Hashimoto, Tatsunori Benjamin (Contributor), Jaakkola, Tommi S. (Contributor), Sherwood, Richard (Author), Mazzoni, Esteban O. (Author), Wichterle, Hynek (Author), Gifford, David K. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Oxford University Press, 2012-12-12T16:46:14Z.
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