Intermolecular Structure Determination of Amyloid Fibrils with 2 Magic-Angle Spinning and Dynamic Nuclear Polarization NMR

Intermolecular Structure Determination of Amyloid Fibrils with 2 Magic-Angle Spinning and Dynamic Nuclear Polarization NMR

We describe magic-angle spinning NMR experiments designed to elucidate the interstrand architecture of amyloid fibrils. Three methods are introduced for this purpose, two being based on the analysis of long-range [superscript 13]C-[superscript 13]C correlation spectra and the third based on the iden...

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Bibliographic Details
Main Authors: Bayro, Marvin J. (Contributor), Debelouchina, Galia Tzvetanova (Contributor), Eddy, Matthew Thomas (Contributor), Birkett, Neil R. (Author), MacPhee, Catherine E. (Author), Rosay, Melanie (Author), Maas, Werner (Author), Dobson, Christopher M. (Author), Griffin, Robert Guy (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor), Francis Bitter Magnet Laboratory (Massachusetts Institute of Technology) (Contributor), Griffin, Robert G. (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2012-11-01T20:43:17Z.
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