Identifying novel constrained elements by exploiting biased substitution patterns
Motivation: Comparing the genomes from closely related species provides a powerful tool to identify functional elements in a reference genome. Many methods have been developed to identify conserved sequences across species; however, existing methods only model conservation as a decrease in the rate...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Oxford University Press (OUP),
2012-09-20T15:11:56Z.
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| Subjects: | |
| Online Access: | Get fulltext |