Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes

Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes

The degeneracy of the genetic code allows protein-coding DNA and RNA sequences to simultaneously encode additional, overlapping functional elements. A sequence in which both protein-coding and additional overlapping functions have evolved under purifying selection should show increased evolutionary...

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Bibliographic Details
Main Authors: Lin, Michael F. (Contributor), Kheradpour, Pouya (Author), Mag Washietl, Stefan (Contributor), Parker, Brian J. (Author), Pedersen, Jakob S. (Author), Kellis, Manolis (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2012-09-19T17:56:09Z.
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