Biased chromatin signatures around polyadenylation sites and exons

Biased chromatin signatures around polyadenylation sites and exons

Core RNA-processing reactions in eukaryotic cells occur cotranscriptionally in a chromatin context, but the relationship between chromatin structure and pre-mRNA processing is poorly understood. We observed strong nucleosome depletion around human polyadenylation sites (PAS) and nucleosome enrichmen...

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Bibliographic Details
Main Authors: Nielsen, Cydney B. (Contributor), Padgett, Richard A. (Author), Spies, Noah (Author), Burge, Christopher B (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Burge, Christopher B. (Contributor), Spies, Noah Walter Benjamin (Contributor)
Format: Article
Language:English
Published: Elsevier, 2012-09-06T18:38:34Z.
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