Compression and self-entanglement of single DNA molecules under uniform electric field

Compression and self-entanglement of single DNA molecules under uniform electric field

We experimentally study the effects of a uniform electric field on the conformation of single DNA molecules. We demonstrate that a moderate electric field (~200 V/cm) strongly compresses isolated DNA polymer coils into isotropic globules. Insight into the nature of these compressed states is gained...

Full description

Bibliographic Details
Main Authors: Tang, Jing (Contributor), Du, Ning (Contributor), Doyle, Patrick S (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Singapore-MIT Alliance in Research and Technology (SMART) (Contributor), Doyle, Patrick S. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2012-06-14T17:47:45Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items