Motor Mechanism for Protein Threading through Hsp104

The protein-remodeling machine Hsp104 dissolves amorphous aggregates as well as ordered amyloid assemblies such as yeast prions. Force generation originates from a tandem AAA+ (ATPases associated with various cellular activities) cassette, but the mechanism and allostery of this action remain to be...

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Bibliographic Details
Main Authors: Wendler, Petra (Author), Shorter, James (Author), Snead, David (Author), Plisson, Celia (Author), Clare, Daniel K. (Author), Saibil, Helen R. (Author), Lindquist, Susan (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Elsevier, 2012-05-25T22:09:00Z.
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