Chemical biology of mutagenesis and DNA repair: cellular responses to DNA alkylation

The reaction of DNA-damaging agents with the genome results in a plethora of lesions, commonly referred to as adducts. Adducts may cause DNA to mutate, they may represent the chemical precursors of lethal events and they can disrupt expression of genes. Determination of which adduct is responsible f...

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Bibliographic Details
Main Authors: Shrivastav, Nidhi (Contributor), Li, Deyu (Contributor), Essigmann, John M. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Essigmann, John (Contributor)
Format: Article
Language:English
Published: Oxford University Press (OUP), 2012-02-15T19:37:24Z.
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