Structure of the EGF receptor transactivation circuit integrates with cell context

Transactivation of the epidermal growth factor receptor (EGFR) is thought to be a process by which a variety of cellular inputs can be integrated into a single signaling pathway through either stimulated proteolysis (shedding) of membrane-anchored EGFR ligands or by modification of the activity of t...

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Bibliographic Details
Main Authors: Joslin, Elizabeth J. (Contributor), Shankaran, Harish (Author), Opresko, Lee K. (Author), Bollinger, Nikki (Author), Lauffenburger, Douglas A. (Contributor), Wiley, H. Steven (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2012-01-23T22:08:23Z.
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