DNA phosphorothioation is widespread and quantized in bacterial genomes

DNA phosphorothioation is widespread and quantized in bacterial genomes

Phosphorothioate (PT) modification of DNA, with sulfur replacing a nonbridging phosphate oxygen, was recently discovered as a product of the dnd genes found in bacteria and archaea. Given our limited understanding of the biological function of PT modifications, including sequence context, genomic fr...

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Bibliographic Details
Main Authors: Wang, Lianrong (Contributor), Chen, Shi (Author), Vergin, Kevin L. (Author), Giovannoni, Stephen J. (Author), Chan, Simon W. (Contributor), DeMott, Michael S. (Contributor), Taghizadeh, Koli (Contributor), Cordero Sanchez, Otto Xavier (Contributor), Cutler, Michael Barry (Contributor), Timberlake, Sonia (Author), Alm, Eric J. (Contributor), Polz, Martin F. (Contributor), Pinhassi, Jarone (Author), Deng, Zixin (Author), Dedon, Peter C. (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Civil and Environmental Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2011-09-30T13:22:48Z.
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