Spatiotemporal controlled delivery of nanoparticles to injured vasculature

Spatiotemporal controlled delivery of nanoparticles to injured vasculature

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There are a number of challenges associated with designing nanoparticles for medical applications. We define two challenges here: (i) conventional targeting against up-regulated cell surface antigens is limited by heterogeneity in expression, and (ii) previous studies suggest that the optimal size o...

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Bibliographic Details
Main Authors: Chan, Juliana Maria (Contributor), Zhang, Liangfang (Author), Tong, Rong (Author), Ghosh, Debadyuti (Contributor), Gao, Weiwei (Author), Liao, Grace V. (Contributor), Yuet, Kai P. (Contributor), Gray, David (Contributor), Rhee, June-Wha (Author), Cheng, Jianjun (Author), Golomb, Gershon (Author), Libby, Peter (Author), Langer, Robert (Contributor), Farokhzad, Omid C. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2011-02-04T12:59:40Z.
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