The Lack of ADAM17 Activity during Embryonic Development Causes Hemorrhage and Impairs Vessel Formation
Background ADAM17/TACE activity is important during embryonic development. We wished to investigate possible roles of this metalloprotease, focusing on vascular development. Methodology/Principal Findings Mice mutant in the enzymatic activity of ADAM17 were examined at various stages of embryonic de...
Main Authors: | , , , , |
---|---|
Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Public Library of Science,
2010-12-22T16:47:09Z.
|
Subjects: | |
Online Access: | Get fulltext |