High-throughput gene expression profiling of memory differentiation in primary human T cells

Background: The differentiation of naive T and B cells into memory lymphocytes is essential for immunity to pathogens. Therapeutic manipulation of this cellular differentiation program could improve vaccine efficacy and the in vitro expansion of memory cells. However, chemical screens to identify co...

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Bibliographic Details
Main Authors: Angelosanto, Jill (Author), Brosnahan, Kathleen (Author), Ross, Kenneth (Contributor), Hahn, Cynthia (Author), Russell, Kate (Author), Drury, Linda (Author), Norton, Stephanie (Contributor), Nadler, Lee (Author), Stegmaier, Kimberly (Contributor), Haining, W. Nicholas (Author)
Other Authors: Broad Institute of MIT and Harvard (Contributor)
Format: Article
Language:English
Published: BioMed Central Ltd, 2010-10-13T15:17:50Z.
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