Creatine kinase pathway inhibition alters GSK3 and WNT signaling in EVI1-positive AML

by Benajiba, Lina, Alexe, Gabriela, Su, Angela, Raffoux, Emmanuel, Soulier, Jean, Hemann, Michael, Hermine, Olivier, Itzykson, Raphael, Stegmaier, Kimberly, Puissant, Alexandre
Published 2020

High-throughput gene expression profiling of memory differentiation in primary human T cells

by Angelosanto, Jill, Brosnahan, Kathleen, Ross, Kenneth, Hahn, Cynthia, Russell, Kate, Drury, Linda, Norton, Stephanie, Nadler, Lee, Stegmaier, Kimberly, Haining, W. Nicholas
Published 2010

EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma

by Iniguez, Amanda Balboni, Stolte, Björn, Wang, Emily Jue, Conway, Amy Saur, Alexe, Gabriela, Dharia, Neekesh V., Kwiatkowski, Nicholas, Zhang, Tinghu, Abraham, Brian J., Mora, Jaume, Kalev, Peter, Leggett, Alan, Chowdhury, Dipanjan, Benes, Cyril H., Gray, Nathanael S., Stegmaier, Kimberly, Young, Richard A.
Published 2019

SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia

by Puissant, Alexandre, Alexe, Gabriela, Pikman, Yana, Bassil, Christopher F, Mehta, Swapnil, Du, Jinyan, Kazi, Julhash U, Luciano, Frédéric, Rönnstrand, Lars, Kung, Andrew L, Aster, Jon C, Galinsky, Ilene, Stone, Richard M, DeAngelo, Daniel J, Stegmaier, Kimberly, Fenouille, Nina, Hemann, Michael
Published 2017

The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia

by Bassil, Christopher F, Ben-Sahra, Issam, Benajiba, Lina, Alexe, Gabriela, Pikman, Yana, Conway, Amy S, Burgess, Michael R, Li, Qing, Luciano, Frédéric, Auberger, Patrick, Galinsky, Ilene, DeAngelo, Daniel J, Stone, Richard M, Zhang, Yi, Perkins, Archibald S, Shannon, Kevin, Puissant, Alexandre, Stegmaier, Kimberly, Fenouille, Nina, Ramos, Azucena, Hemann, Michael
Published 2018

Targeting MTHFD2 in acute myeloid leukemia

by Pikman, Yana, Alexe, Gabriela, Furman, Andrew, Chen, Liying M., Frumm, Stacey M., Ross, Linda, Fenouille, Nina, Bassil, Christopher F., Gould, Joshua, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Clish, Clary B., Kung, Andrew L., Banerji, Versha, Stegmaier, Kimberly, Puissant, Alexandre, Lewis, Caroline, Ramos, Azucena, Hemann, Michael, Vander Heiden, Matthew G.
Published 2017

Targeting MTHFD2 in acute myeloid leukemia

by Pikman, Yana, Puissant, Alexandre, Alexe, Gabriela, Furman, Andrew, Chen, Liying M., Frumm, Stacey M., Ross, Linda, Fenouille, Nina, Bassil, Christopher F., Lewis, Caroline, Ramos, Azucena, Gould, Joshua, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Clish, Clary B., Kung, Andrew L., Hemann, Michael, Vander Heiden, Matthew G., Banerji, Versha, Stegmaier, Kimberly
Published 2022

STAG2 loss reshapes oncogenic enhancer-promoter looping in Ewing sarcoma

by Adane, Biniam, Alexe, Gabriela, Seong, Bo Kyung A., Lu, Diana, Hwang, Elizabeth E., Hnisz, Denes, Lareau, Caleb A., Ross, Linda, Lin, Shan, Dela Cruz, Filemon S., Richardson, Melissa, Weintraub, Abraham Selby, Wang, Sarah, Iniguez, Amanda Balboni, Dharia, Neekesh V., Conway, Amy Saur, Robichaud, Amanda L., Tanenbaum, Benjamin, Krill-Burger, John M., Vazquez, Francisca, Schenone, Monica, Berman, Jason N., Kung, Andrew L., Carr, Steven A., Aryee, Martin J., Young, Richard A., Crompton, Brian D., Stegmaier, Kimberly
Published 2021

In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling

by Miller, Peter G, Al-Shahrour, Fatima, Hartwell, Kimberly A., Chu, Lisa P, Jaras, Marcus, Puram, Rishi V, Puissant, Alexandre, Callahan, Kevin P, Ashton, John, McConkey, Marie, Poveromo, Luke P, Cowley, Glenn S., Kharas, Michael G., Labelle, Myriam, Shterental, Sebastian, Fujisaki, Joji, Silberstein, Lev, Alexe, Gabriela, Al-Hajj, Muhammad A, Shelton, Christopher A, Armstrong, Scott A., Root, David E, Scadden, David T, Mukherjee, Siddhartha, Stegmaier, Kimberly, Jordan, Craig T, Ebert, Benjamin L., Hynes, Richard O
Published 2015

Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma

by Bandopadhayay, Pratiti, Piccioni, Federica, O'Rourke, Ryan, Ho, Patricia, Gonzalez, Elizabeth M., Buchan, Graham, Qian, Kenin, Gionet, Gabrielle, Girard, Emily, Coxon, Margo, Rees, Matthew G., Brenan, Lisa, Dubois, Frank, Shapira, Ofer, Greenwald, Noah F., Pages, Melanie, Balboni Iniguez, Amanda, Paolella, Brenton R., Meng, Alice, Sinai, Claire, Roti, Giovanni, Dharia, Neekesh V., Creech, Amanda, Tanenbaum, Benjamin, Khadka, Prasidda, Tracy, Adam, Tiv, Hong L., Hong, Andrew L., Coy, Shannon, Rashid, Rumana, Lin, Jia-Ren, Cowley, Glenn S., Lam, Fred Chiu-Lai, Goodale, Amy, Lee, Yenarae, Schoolcraft, Kathleen, Vazquez, Francisca, Hahn, William C., Tsherniak, Aviad, Bradner, James E., Yaffe, Michael B, Milde, Till, Pfister, Stefan M., Qi, Jun, Schenone, Monica, Carr, Steven A., Ligon, Keith L., Kieran, Mark W., Santagata, Sandro, Olson, James M., Gokhale, Prafulla C., Jaffe, Jacob D., Root, David E., Stegmaier, Kimberly, Johannessen, Cory M., Beroukhim, Rameen
Published 2020