Fast Microtubule Dynamics in Meiotic Spindles Measured by Single Imaging: Evidence that the Spindle Environment does not Stabilize Microtubules
Metaphase spindles are steady-state ensembles of microtubules that turn over rapidly and slide poleward in some systems. Since the discovery of dynamic instability in the mid-1980s, models for spindle morphogenesis have proposed that microtubules are stabilized by the spindle environment. We used si...
Main Authors: | Mirny, Leonid A. (Contributor), Mitchison, Timothy J. (Author), Maresca, Tom (Author), Ohi, Ryoma (Author), Groen, Aaron (Author), Needleman, Daniel J. (Author) |
---|---|
Other Authors: | Harvard University- (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Society for Cell Biology,
2010-06-03T20:51:10Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
PLD2 regulates microtubule stability and spindle migration in mouse oocytes during meiotic division
by: Xiaoyu Liu, et al.
Published: (2017-05-01) -
The microtubule-associated protein ASPM regulates spindle assembly and meiotic progression in mouse oocytes.
by: Xiao-Ling Xu, et al.
Published: (2012-01-01) -
Visualizing Noncentrosomal Microtubules during Spindle Assembly.
Published: (2004-01-01) -
Connections between microtubules and endoplasmic reticulum in mitotic spindle
by: J. A. Tarkowska
Published: (2015-01-01) -
MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment.
by: Ju Yuan, et al.
Published: (2010-01-01)