Fast Microtubule Dynamics in Meiotic Spindles Measured by Single Imaging: Evidence that the Spindle Environment does not Stabilize Microtubules

Metaphase spindles are steady-state ensembles of microtubules that turn over rapidly and slide poleward in some systems. Since the discovery of dynamic instability in the mid-1980s, models for spindle morphogenesis have proposed that microtubules are stabilized by the spindle environment. We used si...

Full description

Bibliographic Details
Main Authors: Mirny, Leonid A. (Contributor), Mitchison, Timothy J. (Author), Maresca, Tom (Author), Ohi, Ryoma (Author), Groen, Aaron (Author), Needleman, Daniel J. (Author)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: American Society for Cell Biology, 2010-06-03T20:51:10Z.
Subjects:
Online Access:Get fulltext