Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling
Background The understanding of regulatory and signaling networks has long been a core objective in Systems Biology. Knowledge about these networks is mainly of qualitative nature, which allows the construction of Boolean models, where the state of a component is either 'off' or 'on...
Main Authors: | Wittmann, Dominik M. (Author), Krumsiek, Jan (Author), Saez-Rodriguez, Julio (Contributor), Lauffenburger, Douglas A. (Contributor), Klamt, Steffen (Author), Theis, Fabian J. (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd.,
2010-03-04T19:51:46Z.
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Subjects: | |
Online Access: | Get fulltext |
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