Antibodies specifically targeting a locally misfolded region of tumor associated EGFR

Antibodies specifically targeting a locally misfolded region of tumor associated EGFR

Epidermal Growth Factor Receptor (EGFR) is involved in stimulating the growth of many human tumors, but the success of therapeutic agents has been limited in part by interference from the EGFR on normal tissues. Previously, we reported an antibody (mab806) against a truncated form of EGFR found comm...

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Main Authors: Garrett, Thomas P. J. (Author), Burgess, Anthony W. (Author), Gan, Hui K. (Author), Luwor, Rod B. (Author), Cartwright, Glenn (Author), Walker, Francesca (Author), Orchard, Suzanne G. (Author), Clayton, Andrew H. A. (Author), Nice, Edouard C. (Author), Rothacker, Julie (Author), Catimel, Bruno (Author), Cavenee, Webster K. (Author), Old, Lloyd J. (Author), Stockert, Elisabeth (Author), Ritter, Gerd (Author), Adams, Timothy E. (Author), Hoyne, Peter A. (Author), Wittrup, Karl Dane (Contributor), Chao, Ginger (Contributor), Cochran, Jennifer R. (Contributor), Lou, Cindy (Author), Lou, Mezhen (Author), Huyton, Trevor (Author), Xu, Yibin (Author), Fairlie, W. Douglas (Author), Yao, Shenggen (Author), Scott, Andrew M. (Author), Johns, Terrance G. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2009-12-28T16:48:30Z.
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