An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy

Monoclonal antibodies targeted to the programmed cell death protein 1 (PD-1) remain the most prevalent cancer immunotherapy both as a monotherapy and in combination with additional therapies. Despite the extensive success of anti-PD-1 monoclonal antibodies in the clinic, the experimental relationshi...

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Bibliographic Details
Main Authors: Cowles, Sarah C. (Author), Sheen, Allison (Author), Santollani, Luciano (Author), Lutz, Emi A. (Author), Lax, Brianna M. (Author), Palmeri, Joseph R. (Author), Freeman, Gordon J. (Author), Wittrup, K. Dane (Author)
Format: Article
Language:English
Published: Taylor & Francis, 2022-08-09T14:40:28Z.
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