Selective Permeabilization of Gram-Negative Bacterial Membranes Using Multivalent Peptide Constructs for Antibiotic Sensitization
The drug-impermeable bacterial membrane in Gram-negative pathogens limits antibiotic access to intracellular drug targets. To expand our rapidly waning antibiotic arsenal, one approach is to improve the intracellular delivery of drugs with historically poor accumulation in Gram-negative bacteria. To...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2022-06-01T19:38:51Z.
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Subjects: | |
Online Access: | Get fulltext |