Enantioselective C2-Allylation of Benzimidazoles Using 1,3-Diene Pronucleophiles

Although substituted benzimidazoles are common substructures in bioactive small molecules, synthetic methods for their derivatization are still limited. Previously, several enantioselective allylation reactions of benzimidazoles were reported that functionalize the nucleophilic nitrogen atom. Herein...

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Bibliographic Details
Main Authors: Knippel, James Levi (Author), Ye, Yuxuan (Author), Buchwald, Stephen L (Author)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2022-03-30T17:54:15Z.
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