Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors

Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors

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Oral administration provides a simple and non-invasive approach for drug delivery. However, due to poor absorption and swift enzymatic degradation in the gastrointestinal tract, a wide range of molecules must be parenterally injected to attain required doses and pharmacokinetics. Here we present an...

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Main Authors: Abramson, Alex (Author), Frederiksen, Morten Revsgaard (Author), Vegge, Andreas (Author), Jensen, Brian (Author), Poulsen, Mette (Author), Mouridsen, Brian (Author), Jespersen, Mikkel Oliver (Author), Kirk, Rikke Kaae (Author), Windum, Jesper (Author), Hubálek, František (Author), Water, Jorrit J (Author), Fels, Johannes (Author), Gunnarsson, Stefán B (Author), Bohr, Adam (Author), Straarup, Ellen Marie (Author), Ley, Mikkel Wennemoes Hvitfeld (Author), Lu, Xiaoya (Author), Wainer, Jacob (Author), Collins, Joy (Author), Tamang, Siddartha (Author), Ishida, Keiko (Author), Hayward, Alison (Author), Herskind, Peter (Author), Buckley, Stephen T (Author), Roxhed, Niclas (Author), Langer, Robert (Author), Rahbek, Ulrik (Author), Traverso, Giovanni (Author)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2022-03-29T18:45:57Z.
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