Machine learning modeling of family wide enzyme-substrate specificity screens

Biocatalysis is a promising approach to sustainably synthesize pharmaceuticals, complex natural products, and commodity chemicals at scale. However, the adoption of biocatalysis is limited by our ability to select enzymes that will catalyze their natural chemical transformation on non-natural substr...

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Bibliographic Details
Main Authors: Goldman, Samuel (Author), Das, Ria (Author), Yang, Kevin K (Author), Coley, Connor Wilson (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Public Library of Science (PLoS), 2022-07-12T20:43:04Z.
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