A concise route to MK-4482 (EIDD-2801) from cytidine
© The Royal Society of Chemistry. A two-step route to MK-4482 (EIDD-2801, 1) was developed consisting of an esterification and hydroxamination of cytidine. The selective acylation and direct amination eliminate the need for protecting and activating groups and proceed in overall yield of 75%, a sign...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry (RSC),
2022-03-09T15:25:53Z.
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| Subjects: | |
| Online Access: | Get fulltext |