Binding Sites of a Positron Emission Tomography Imaging Agent in Alzheimer's β-Amyloid Fibrils Studied Using 19F Solid-State NMR

Amyloid imaging by positron emission tomography (PET) is an important method for diagnosing neurodegenerative disorders such as Alzheimer's disease. Many 11C- and 18F-labeled PET tracers show varying binding capacities, specificities, and affinities for their target proteins. The structural bas...

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Bibliographic Details
Main Authors: Duan, Pu (Author), Chen, Kelly J (Author), Wijegunawardena, Gayani (Author), Dregni, Aurelio J (Author), Wang, Harrison K (Author), Wu, Haifan (Author), Hong, Mei (Author)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2022-03-09T14:54:21Z.
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