Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers
An essential protein of the SARS-CoV-2 virus, the envelope protein E, forms a homopentameric cation channel that is important for virus pathogenicity. Here we report a 2.1-Å structure and the drug-binding site of E's transmembrane domain (ETM), determined using solid-state NMR spectroscopy. In...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC,
2022-03-08T20:31:03Z.
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Subjects: | |
Online Access: | Get fulltext |