Gap junctions amplify spatial variations in cell volume in proliferating tumor spheroids
© 2020, The Author(s). Sustained proliferation is a significant driver of cancer progression. Cell-cycle advancement is coupled with cell size, but it remains unclear how multiple cells interact to control their volume in 3D clusters. In this study, we propose a mechano-osmotic model to investigate...
Main Authors: | , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC,
2021-12-21T23:01:27Z.
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Subjects: | |
Online Access: | Get fulltext |