Gap junctions amplify spatial variations in cell volume in proliferating tumor spheroids

© 2020, The Author(s). Sustained proliferation is a significant driver of cancer progression. Cell-cycle advancement is coupled with cell size, but it remains unclear how multiple cells interact to control their volume in 3D clusters. In this study, we propose a mechano-osmotic model to investigate...

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Bibliographic Details
Main Authors: McEvoy, Eoin (Author), Han, Yu Long (Author), Guo, Ming (Author), Shenoy, Vivek B (Author)
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2021-12-21T23:01:27Z.
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