The influence of the gut microbiome on BCG-induced trained immunity

The influence of the gut microbiome on BCG-induced trained immunity

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Abstract Background The bacillus Calmette-Guérin (BCG) vaccine protects against tuberculosis and heterologous infections but elicits high inter-individual variation in specific and nonspecific, or trained, immune responses. While the gut microbiome is increasingly recognized as an important modulat...

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Main Authors: Stražar, Martin (Author), Mourits, Vera P. (Author), Koeken, Valerie A. C. M. (Author), de Bree, L. C. J. (Author), Moorlag, Simone J. C. F. M. (Author), Joosten, Leo A. B. (Author), van Crevel, Reinout (Author), Vlamakis, Hera (Author), Netea, Mihai G. (Author), Xavier, Ramnik J. (Author)
Format: Article
Language:English
Published: BioMed Central, 2022-01-24T14:34:47Z.
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