A mechanistic compartmental model for total antibody uptake in tumors
Antibodies are under development to treat a variety of cancers, such as lymphomas, colon, and breast cancer. A major limitation to greater efficacy for this class of drugs is poor distribution in vivo. Localization of antibodies occurs slowly, often in insufficient therapeutic amounts, and distribut...
Main Authors: | , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Elsevier BV,
2022-07-12T15:31:22Z.
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Subjects: | |
Online Access: | Get fulltext |