Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors

<p>We identified potent, functionalisable BMX inhibitors and revealed their covalent mode of binding to BMX by X-ray crystallography.</p>

Bibliographic Details
Main Authors:	Seixas, João D (Author), Sousa, Bárbara B (Author), Marques, Marta C (Author), Guerreiro, Ana (Author), Traquete, Rui (Author), Rodrigues, Tiago (Author), Albuquerque, Inês S (Author), Sousa, Marcos FQ (Author), Lemos, Ana R (Author), Sousa, Pedro MF (Author), Bandeiras, Tiago M (Author), Wu, Di (Author), Doyle, Shelby K (Author), Robinson, Carol V (Author), Koehler, Angela N (Author), Corzana, Francisco (Author), Matias, Pedro M (Author), Bernardes, Gonçalo JL (Author)
Format:	Article
Language:	English
Published:	Royal Society of Chemistry (RSC), 2022-01-24T15:14:08Z.
Subjects:	Article
Online Access:	Get fulltext

Get fulltext

Similar Items