Oncogenic HSP90 facilitates metabolic alterations in aggressive B-cell lymphomas

Oncogenic HSP90 facilitates metabolic alterations in aggressive B-cell lymphomas

HSP90 is critical for the maintenance of cellular proteostasis. In cancer cells, HSP90 also becomes a nucleating site for the stabilization of multiprotein complexes including signaling pathways and transcription complexes. Here we describe the role of this HSP90 form, referred to as oncogenic HSP90...

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Main Authors: Calvo-Vidal, M Nieves (Author), Zamponi, Nahuel (Author), Krumsiek, Jan (Author), Stockslager, Max A (Author), Revuelta, Maria V (Author), Phillip, Jude M (Author), Marullo, Rossella (Author), Tikhonova, Ekaterina (Author), Kotlov, Nikita (Author), Patel, Jayeshkumar (Author), Yang, Shao Ning (Author), Yang, Lucy (Author), Taldone, Tony (Author), Thieblemont, Catherine (Author), Leonard, John P (Author), Martin, Peter (Author), Inghirami, Giorgio (Author), Chiosis, Gabriela (Author), Manalis, Scott R (Author), Cerchietti, Leandro (Author)
Format: Article
Language:English
Published: American Association for Cancer Research (AACR), 2021-10-15T13:56:42Z.
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