Alternative Splicing of FN (Fibronectin) Regulates the Composition of the Arterial Wall Under Low Flow

Objective: Exposure of the arterial endothelium to low and disturbed flow is a risk factor for the erosion and rupture of atherosclerotic plaques and aneurysms. Circulating and locally produced proteins are known to contribute to an altered composition of the extracellular matrix at the site of lesi...

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Bibliographic Details
Main Authors: Murphy, Patrick Andries (Author), Jailkhani, Noor (Author), Nicholas, Sarah-Anne (Author), Del Rosario, Amanda M (Author), Balsbaugh, Jeremy L. (Author), Begum, Shahinoor (Author), Kimble, Amy (Author), Hynes, Richard O (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Ovid Technologies (Wolters Kluwer Health), 2021-08-10T20:43:54Z.
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