Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors

Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors

In vitro gametogenesis is the process of making germline cells from human pluripotent stem cells. The foundation of this model is the quality of the first progenitors called primordial germ cells (PGCs), which in vivo are specified during the peri-implantation window of human development. Here, we s...

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Main Authors: Chen, Di (Author), Sun, Na (Author), Hou, Lei (Author), Kim, Rachel (Author), Faith, Jared (Author), Aslanyan, Marianna (Author), Tao, Yu (Author), Zheng, Yi (Author), Fu, Jianping (Author), Liu, Wanlu (Author), Kellis, Manolis (Author), Clark, Amander (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2021-01-08T16:45:54Z.
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