Low Doses of Arsenic in a Mouse Model of Human Exposure and in Neuronal Culture Lead to S-Nitrosylation of Synaptic Proteins and Apoptosis via Nitric Oxide

Low Doses of Arsenic in a Mouse Model of Human Exposure and in Neuronal Culture Lead to S-Nitrosylation of Synaptic Proteins and Apoptosis via Nitric Oxide

Background: Accumulating public health and epidemiological literature support the hypothesis that arsenic in drinking water or food affects the brain adversely. Methods: Experiments on the consequences of nitric oxide (NO) formation in neuronal cell culture and mouse brain were conducted to probe th...

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Main Authors: Amal, Haitham (Author), Gong, Guanyu (Author), Yang, Hongmei (Author), Joughin, Brian A. (Author), Wang, Xin (Author), Knutson, Charles G. F. (Author), Kartawy, Maryam (Author), Khaliulin, Igor (Author), Wishnok, John S. (Author), Tannenbaum, Steven R (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Multidisciplinary Digital Publishing Institute, 2020-08-24T17:47:21Z.
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