Selection Has Countered High Mutability to Preserve the Ancestral Copy Number of Y Chromosome Amplicons in Diverse Human Lineages

Amplicons-large, highly identical segmental duplications-are a prominent feature of mammalian Y chromosomes. Although they encode genes essential for fertility, these amplicons differ vastly between species, and little is known about the selective constraints acting on them. Here, we develop computa...

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Bibliographic Details
Main Authors: Teitz, Levi Shmuel (Author), Pyntikova, Tatyana (Author), Skaletsky, Helen (Author), Page, David C (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2020-07-28T15:36:35Z.
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