Selection Has Countered High Mutability to Preserve the Ancestral Copy Number of Y Chromosome Amplicons in Diverse Human Lineages
Amplicons-large, highly identical segmental duplications-are a prominent feature of mammalian Y chromosomes. Although they encode genes essential for fertility, these amplicons differ vastly between species, and little is known about the selective constraints acting on them. Here, we develop computa...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier BV,
2020-07-28T15:36:35Z.
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Subjects: | |
Online Access: | Get fulltext |