Deploying Fluorescent Nucleoside Analogues for High‐Throughput Inhibitor Screening

High-throughput small-molecule screening in drug discovery processes commonly rely on fluorescence-based methods including fluorescent polarization and fluorescence/Förster resonance energy transfer. These techniques use highly accessible instrumentation; however, they can suffer from high false-ne...

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Bibliographic Details
Main Authors: Seebald, Leah (Author), Madec, Amael (Author), Imperiali, Barbara (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Wiley, 2020-07-20T21:12:32Z.
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