Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation

Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation

Purpose: Despite the accumulation of extensive genomic alterations, many cancers fail to be recognized as "foreign" and escape destruction by the host immune system. Immunotherapies designed to address this problem by directly stimulating immune effector cells have led to some remarkable c...

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Bibliographic Details
Main Authors: Jaeger, Alex M. (Author), Stopfer, Lauren Elizabeth (Author), Lee, Sunmin (Author), Gaglia, Giorgio (Author), Sandel, Demi (Author), Santagata, Sandro (Author), Lin, Nancy U. (Author), Trepel, Jane B. (Author), White, Forest M. (Author), Jacks, Tyler E (Author), Lindquist, Susan (Author), Whitesell, Luke (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Association for Cancer Research (AACR), 2020-05-29T15:21:37Z.
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