Dynamic Clustering Regulates Activity of Mechanosensitive Membrane Channels

Experiments have suggested that bacterial mechanosensitive channels separate into 2D clusters, the role of which is unclear. By developing a coarse-grained computer model we find that clustering promotes the channel closure, which is highly dependent on the channel concentration and membrane stress....

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Bibliographic Details
Main Authors: Paraschiv, Alexandru (Author), Hegde, Smitha (Author), Ganti, Raman (Author), Pilizota, Teuta (Author), Šarić, Anđela (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor)
Format: Article
Language:English
Published: American Physical Society (APS), 2020-05-27T19:23:59Z.
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