Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements
Cancer genomes are frequently characterized by numerical and structural chromosomal abnormalities. Here we integrated a centromere-specific inactivation approach with selection for a conditionally essential gene, a strategy termed CEN-SELECT, to systematically interrogate the structural landscape of...
| Main Authors: | , |
|---|---|
| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media LLC,
2020-05-07T17:29:50Z.
|
| Subjects: | |
| Online Access: | Get fulltext |