Altered exocrine function can drive adipose wasting in early pancreatic cancer

Altered exocrine function can drive adipose wasting in early pancreatic cancer

Changes in cell and organismal metabolism accompany malignancy1,2. Pancreatic ductal adenocarcinoma (PDAC) is associated with peripheral tissue wasting, a metabolic syndrome that lowers quality of life and is proposed to decrease cancer patient survival3,4. Tissue wasting is a multifactorial disease...

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Bibliographic Details
Main Authors: Danai, Laura V. (Author), Dennstedt, Emily A. (Author), Muir, Alexander (Author), Lien, Evan C. (Author), Mayers, Jared R. (Author), Lau, Allison N. (Author), Jones-Sali, Paul (Author), Vander Heiden, Matthew G. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2020-04-29T16:19:25Z.
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