Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry
Childhood high-risk neuroblastomas with MYCN gene amplification are difficult to treat effectively 1 . This has focused attention on tumor-specific gene dependencies that underlie tumorigenesis and thus provide valuable targets for the development of novel therapeutics. Using unbiased genome-scale C...
| Main Authors: | , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media LLC,
2020-04-29T14:41:43Z.
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| Subjects: | |
| Online Access: | Get fulltext |