Balance of mechanical forces drives endothelial gap formation and may facilitate cancer and immune-cell extravasation

The formation of gaps in the endothelium is a crucial process underlying both cancer and immune cell extravasation, contributing to the functioning of the immune system during infection, the unfavorable development of chronic inflammation and tumor metastasis. Here, we present a stochastic-mechanica...

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Bibliographic Details
Main Authors: Escribano, Jorge (Author), Chen, Michelle B. (Author), Moeendarbary, Emad (Author), Kamm, Roger D. (Author), Spill, Fabian (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Public Library of Science (PLoS), 2020-04-02T18:50:21Z.
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