Mutations in pmrB Confer Cross-Resistance between the LptD Inhibitor POL7080 and Colistin in Pseudomonas aeruginosa
Pseudomonas aeruginosa is a major bacterial pathogen associated with a rising prevalence of antibiotic resistance. We evaluated the resistance mechanisms of P. aeruginosa against POL7080, a species-specific, first-in-class antibiotic in clinical trials that targets the lipopolysaccharide transport p...
| Main Authors: | , , , , , , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology,
2020-01-14T16:45:36Z.
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| Subjects: | |
| Online Access: | Get fulltext |