Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning

A varying oxygen environment is known to affect cellular function in disease as well as activity of various therapeutics. For transient structures, whether they are unconstrained therapeutic transplants, migrating cells during tumor metastasis, or cell populations induced by an immunological respons...

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Bibliographic Details
Main Authors: Spanoudaki, Virginia (Author), Doloff, Joshua C (Author), Huang, Wei (Author), Norcross, Samuel (Author), Farah, Shady (Author), Langer, Robert S (Author), Anderson, Daniel Griffith (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences, 2019-08-30T14:49:14Z.
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