Rational engineering of Escherichia coli strains for plasmid biopharmaceutical manufacturing

Plasmid DNA (pDNA) has become very attractive as a biopharmaceutical, especially for gene therapy and DNA vaccination. Currently, there are a few products licensed for veterinary applications and numerous plasmids in clinical trials for use in humans. Recent work in both academia and industry demons...

Full description

Bibliographic Details
Main Authors: Gonçalves, Geisa A. L. (Author), Bower, Diana Morgan (Author), Prazeres, Duarte M. F. (Author), Monteiro, Gabriel A. (Author), Jones, Kristala L. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Wiley, 2019-07-18T18:36:10Z.
Subjects:
Online Access:Get fulltext