Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute-phase Toxoplasma gondii burden

Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute-phase Toxoplasma gondii burden

We generated a CD8 T-cell receptor (TCR) transnuclear (TN) mouse specific to the Ld-restricted immunodominant epitope of GRA6 from Toxoplasma gondii as a source of cells to facilitate further investigation into the CD8 T-cell-mediated response against this pathogen. The TN T cells bound Ld-Gra6 tetr...

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Main Authors: Sanecka, Anna (Author), Yoshida, Nagisa (Author), Dougan, Stephanie K. (Author), Jackson, John (Author), Shastri, Nilabh (Author), Ploegh, Hidde (Author), Blanchard, Nicolas (Author), Frickel, Eva-Maria (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Wiley, 2019-06-17T18:39:49Z.
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