High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human

High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human

Genome-wide epigenomic maps have revealed millions of putative enhancers and promoters, but experimental validation of their function and high-resolution dissection of their driver nucleotides remain limited. Here, we present HiDRA (High-resolution Dissection of Regulatory Activity), a combined expe...

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Main Authors: Goggin, Sarah M. (Author), Saadat, Alham (Author), Wang, Li (Author), Sinnott-Armstrong, Nasa (Author), Wang, Xinchen (Contributor), He, Liang (Contributor), Kellis, Manolis (Contributor), Claussnitzer, Melina (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Claussnitzer, MelinaChristine (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2019-03-26T15:50:59Z.
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