Positional specificity of different transcription factor classes within enhancers
Gene expression is controlled by sequence-specific transcription factors (TFs), which bind to regulatory sequences in DNA. TF binding occurs in nucleosome-depleted regions of DNA (NDRs), which generally encompass regions with lengths similar to those protected by nucleosomes. However, less is known...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
National Academy of Sciences (U.S.),
2019-02-22T17:52:06Z.
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Subjects: | |
Online Access: | Get fulltext |