Interstitial flow promotes macrophage polarization toward an M2 phenotype

Interstitial flow promotes macrophage polarization toward an M2 phenotype

Tumor tissues are characterized by an elevated interstitial fluid flow from the tumor to the surrounding stroma. Macrophages in the tumor microenvironment are key contributors to tumor progression. While it is well established that chemical stimuli within the tumor tissues can alter macrophage behav...

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Bibliographic Details
Main Authors: Serrano, Jean Carlos (Author), Zaman, Muhammad (Author), Li, Ran (Contributor), Xing, Hao (Contributor), Lee, Tara A. (Contributor), Azizgolshani, Hesham (Contributor), Kamm, Roger Dale (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: American Society for Cell Biology, 2018-12-07T14:58:59Z.
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